Vitiligo is a skin disorder characterized by the loss of pigmentation, resulting in white patches on the skin. While there is no cure for vitiligo, several treatments and ingredients may help manage the condition and potentially restore pigment to affected areas. Here are the top 10 ingredients commonly used to treat vitiligo, along with brief descriptions of their benefits:

Topical Corticosteroids

These prescription medications can help suppress the immune response that attacks melanocytes (pigment-producing cells) in vitiligo-affected areas, potentially slowing the progression of the condition.

Topical Calcineurin Inhibitors (Tacrolimus, Pimecrolimus)

Calcineurin inhibitors are prescription creams that can help regulate the immune response and reduce inflammation in vitiligo-affected skin, potentially promoting repigmentation.

Psoralen with Ultraviolet A (PUVA) Therapy

PUVA therapy combines the use of psoralen (a light-sensitizing medication) with UVA exposure to stimulate melanocyte activity and encourage repigmentation.

Narrowband Ultraviolet B (NB-UVB) Therapy

NB-UVB therapy involves exposure to specific wavelengths of UVB light, which can stimulate melanocyte function and promote repigmentation in vitiligo patches.

Protopic (Tacrolimus) Ointment

Protopic is a topical calcineurin inhibitor that can help manage vitiligo by reducing inflammation and potentially promoting repigmentation.

Excimer Laser

The excimer laser delivers a high-intensity, focused beam of UVB light to vitiligo patches, which can stimulate melanocyte activity and repigmentation.

Vitamin D Analogues (Calcitriol)

Topical calcitriol can help regulate skin cell growth and may be used in combination with other treatments to encourage repigmentation in vitiligo.


Khellin is a plant-derived compound that has been studied for its potential to stimulate melanocyte activity and repigmentation in vitiligo.

Corticosteroid Injections

Intralesional corticosteroid injections can be administered by a dermatologist to reduce inflammation and potentially encourage repigmentation in localized vitiligo patches.

Melanocyte Transplantation

In this advanced procedure, melanocytes are transplanted from unaffected areas of the patient's skin to vitiligo-affected areas, promoting repigmentation.

It's important to note that treatment outcomes for vitiligo can vary widely among individuals, and not all treatments are effective for everyone. Additionally, these treatments may require ongoing maintenance to maintain repigmentation. Consultation with a dermatologist is crucial to determine the most suitable treatment approach based on the type, location, and extent of vitiligo.